ICD-10-CM 2027
ICD-10 code for cardiovascular atherosclerotic disease
Atherosclerotic heart disease of native coronary artery without angina pectoris
From the official ICD-10-CM alphabetic index entry “Disease, diseased › cardiovascular (atherosclerotic)”. Page updated September 29, 2026.
About coding cardiovascular atherosclerotic disease
The ICD-10-CM code for cardiovascular atherosclerotic disease is I25.10 (Atherosclerotic heart disease of native coronary artery without angina pectoris). The official index lists 4 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on I25.10.
Within I25.1, choose I25.10 (without angina pectoris) only when documentation doesn't support a more specific option: with angina pectoris (I25.11).
Use an additional code to identify: chronic total occlusion of coronary artery (I25.82), exposure to environmental tobacco smoke (Z77.22), history of tobacco dependence (Z87.891), occupational exposure to environmental tobacco smoke (Z57.31), tobacco dependence (F17.-) and 1 more.
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
More specific cardiovascular atherosclerotic disease codes (official index)
- with angina pectoris
- congenital Q28.9 — Congenital malformation of circulatory system, unspecified
- newborn P29.9 — Cardiovascular disorder originating in the perinatal period, unspecified
- specified NEC P29.89 — Other cardiovascular disorders originating in the perinatal period
- hypertensive
- renal (hypertensive)
- syphilitic (asymptomatic) A52.00 — Cardiovascular syphilis, unspecified
Common questions about cardiovascular atherosclerotic disease ICD-10 codes
What is the ICD-10 code for cardiovascular atherosclerotic disease?
- I25.10 — Atherosclerotic heart disease of native coronary artery without angina pectoris. More specific codes apply when the documentation supports them: Q28.9, P29.9, P29.89, A52.00.
What is the ICD-10 code for congenital cardiovascular atherosclerotic disease?
- Q28.9 — Congenital malformation of circulatory system, unspecified.
What is the ICD-10 code for newborn cardiovascular atherosclerotic disease?
- P29.9 — Cardiovascular disorder originating in the perinatal period, unspecified.
What is the ICD-10 code for syphilitic cardiovascular atherosclerotic disease?
- A52.00 — Cardiovascular syphilis, unspecified.
Is I25.10 billable?
- Yes. I25.10 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can I25.10 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict I25.10 as a principal diagnosis.
Is I25.10 a CC or MCC?
- No. I25.10 is neither a CC nor an MCC under MS-DRG v44.0.