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ICD-10-CM 2027

ICD-10 code for antidepressant discontinuation syndrome

T43.205

Adverse effect of unspecified antidepressants

Header — needs a more specific code

From the official ICD-10-CM alphabetic index entry “Syndrome › antidepressant discontinuation”. Page updated September 29, 2026.

About coding antidepressant discontinuation syndrome

The ICD-10-CM code for antidepressant discontinuation syndrome is T43.205 (Adverse effect of unspecified antidepressants).

Within T43.20, choose T43.205 (Adverse effect of unspecified antidepressants) only when documentation doesn't support a more specific option: poisoning by unspecified antidepressants, accidental (unintentional) (T43.201), poisoning by unspecified antidepressants, intentional self-harm (T43.202), poisoning by unspecified antidepressants, assault (T43.203), poisoning by unspecified antidepressants, undetermined (T43.204) and underdosing of unspecified antidepressants (T43.206).

Codes in this range require a 7th character: A for initial encounter, D for subsequent encounter and S for sequela. Use placeholder "X" characters to fill any empty positions before the 7th character.

It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.

Common questions about antidepressant discontinuation syndrome ICD-10 codes

What is the ICD-10 code for antidepressant discontinuation syndrome?

T43.205 — Adverse effect of unspecified antidepressants (a header code; report a more specific subcode).

Is T43.205 billable?

No. T43.205 is a header code. Report one of its more specific subcodes instead.