ICD-10-CM 2027
ICD-10 code for acute promyelocytic leukemia
From the official ICD-10-CM alphabetic index entry “Leukemia, leukemic › acute promyelocytic”. Page updated September 29, 2026.
About coding acute promyelocytic leukemia
The ICD-10-CM code for acute promyelocytic leukemia is C92.4 (Acute promyelocytic leukemia).
Within C92 (myeloid leukemia), C92.4 is specifically for acute promyelocytic leukemia. Related codes cover acute myeloblastic leukemia (C92.0), chronic myeloid leukemia, BCR/ABL-positive (C92.1), atypical chronic myeloid leukemia, BCR/ABL-negative (C92.2), myeloid sarcoma (C92.3), acute myelomonocytic leukemia (C92.5), acute myeloid leukemia with 11q23-abnormality (C92.6), unspecified (C92.9), acute myeloid leukemia with multilineage dysplasia (C92.A) and 1 more.
To report this condition, pick the subcode that matches the documentation: C92.40 (not having achieved remission), C92.41 (in remission) and C92.42 (in relapse).
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.