Skip to content
Dx

ICD-10-CM 2027

ICD-10 code for acute on chronic graft-versus-host disease

D89.812

Acute on chronic graft-versus-host disease

From the official ICD-10-CM alphabetic index entry “Graft-versus-host disease › acute on chronic”. Page updated September 29, 2026.

About coding acute on chronic graft-versus-host disease

The ICD-10-CM code for acute on chronic graft-versus-host disease is D89.812 (Acute on chronic graft-versus-host disease).

Within D89.81 (graft-versus-host disease), D89.812 is specifically for acute on chronic graft-versus-host disease. Related codes cover acute graft-versus-host disease (D89.810), chronic graft-versus-host disease (D89.811) and unspecified (D89.813).

As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.

In MS-DRG v44.0, it is part of the grouping logic for DRG 808 (Major Hematological and Immunological Diagnoses Except Sickle Cell Crisis and Coagulation Disorders with MCC, relative weight 2.1705), DRG 809 (Major Hematological and Immunological Diagnoses Except Sickle Cell Crisis and Coagulation Disorders with CC, relative weight 1.2262) and DRG 810 (Major Hematological and Immunological Diagnoses Except Sickle Cell Crisis and Coagulation Disorders without CC/MCC, relative weight 1.075), in MDC 16 (Diseases and Disorders of the Blood and Blood Forming Organs and Immunological Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

Common questions about acute on chronic graft-versus-host disease ICD-10 codes

What is the ICD-10 code for acute on chronic graft-versus-host disease?

D89.812 — Acute on chronic graft-versus-host disease.

Is D89.812 billable?

Yes. D89.812 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can D89.812 be used as a principal diagnosis?

No. It is not acceptable as the principal diagnosis for an inpatient stay; it may be reported as a secondary diagnosis.

Is D89.812 a CC or MCC?

D89.812 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.