ICD-10-CM 2027
ICD-10 code for acidemia
From the official ICD-10-CM alphabetic index entry “Acidemia”. Page updated September 29, 2026.
About coding acidemia
The ICD-10-CM code for acidemia is E87.20 (Acidosis, unspecified). The official index lists 9 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on E87.20.
Within E87.2, choose E87.20 (unspecified) only when documentation doesn't support a more specific option: acute metabolic acidosis (E87.21), chronic metabolic acidosis (E87.22) and other acidosis (E87.29).
As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.
In MS-DRG v44.0, it is part of the grouping logic for DRG 640 (Miscellaneous Disorders of Nutrition, Metabolism, Fluids and Electrolytes with MCC, relative weight 1.3395), DRG 641 (Miscellaneous Disorders of Nutrition, Metabolism, Fluids and Electrolytes without MCC, relative weight 0.7865), DRG 791 (Prematurity with Major Problems, relative weight 4.1075) and DRG 793 (Full Term Neonate with Major Problems, relative weight 4.2195), in MDC 10 (Endocrine, Nutritional and Metabolic Diseases and Disorders) and MDC 15 (Newborns and Other Neonates with Conditions Originating in the Perinatal Period), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
More specific acidemia codes (official index)
- argininosuccinic E72.22 — Arginosuccinic aciduria
- isovaleric E71.110 — Isovaleric acidemia
- metabolic
- newborn P19.9 — Metabolic acidemia in newborn, unspecified
- first noted before onset of labor P19.0 — Metabolic acidemia in newborn first noted before onset of labor
- first noted during labor P19.1 — Metabolic acidemia in newborn first noted during labor
- noted at birth P19.2 — Metabolic acidemia noted at birth
- methylmalonic E71.120 — Methylmalonic acidemia
- pipecolic E72.3 — Disorders of lysine and hydroxylysine metabolism
- propionic E71.121 — Propionic acidemia
Common questions about acidemia ICD-10 codes
What is the ICD-10 code for acidemia?
- E87.20 — Acidosis, unspecified. More specific codes apply when the documentation supports them: E72.22, E71.110, P19.9, P19.0 and others below.
What is the ICD-10 code for argininosuccinic acidemia?
- E72.22 — Arginosuccinic aciduria.
What is the ICD-10 code for isovaleric acidemia?
- E71.110 — Isovaleric acidemia.
What is the ICD-10 code for methylmalonic acidemia?
- E71.120 — Methylmalonic acidemia.
What is the ICD-10 code for pipecolic acidemia?
- E72.3 — Disorders of lysine and hydroxylysine metabolism.
What is the ICD-10 code for propionic acidemia?
- E71.121 — Propionic acidemia.
Is E87.20 billable?
- Yes. E87.20 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can E87.20 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict E87.20 as a principal diagnosis.
Is E87.20 a CC or MCC?
- E87.20 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.